Searchable abstracts of presentations at key conferences in endocrinology

ea0013p125 | Growth and development | SFEBES2007

Inflammatory cytokines in juvenile idiopathic arthritis: Effects on physical growth and in vitro longitudinal bone growth

Wong SC , MacRae VE , Smith W , Gracie JA , McInnes IB , Galea P , Gardner-Medwin J , Ahmed SF

Background: Inflammatory cytokines in children with juvenile idiopathic arthritis (JIA) may modulate growth through systemic and local mechanisms.Aims: To study the relationship between inflammatory cytokines in serum /synovial fluid (SF) with growth and to assess the effects of serum/SF on the fetal rat metatarsal model.Subjects & Methods: 17 children with JIA (F,10): 8 oligoarticular, 2 extended oligoarticular, 6 polyarticula...